Vacuum-assisted Closure Vs Conventional Open Treatment in Diabetic Foot Ulcer - A Comparative Study
Keywords:diabetic foot ulcer, infections, conventional dressings, vacuum-assisted closure, wound closure
Background: Vacuum-assisted closure (VAC) therapy also called negative pressure wound therapy (NPWT) is an emerging therapeutic option for diabetic foot ulcers. So, the current study intends to compare vacuum-assisted closure therapy and conventional open therapy in diabetic foot ulcers.
Methods: A prospective case-control study was conducted and 54 patients were randomly allotted into 2 groups during the study period. The cases group includes patients undergone VAC therapy and the control group includes patients undergone conventional open therapy.
Results: Patients in Group A had fewer positive wound cultures and secondary amputations as compared to Group B. VAC therapy was found to considerably improve the meantime to complete wound healing (24.22 days vs. 32.66 days). Secondary amputations were performed on 0% of patients in group A and 11.11 percent of patients in group B. The average hospital stay for group A was 20.33 days and 26.77 days for group B.
Conclusion: When compared to standard dressing, VAC treatment considerably lowers the time to complete wound healing, accelerates granulation tissue production, and reduces ulcer area. The VAC treatment group had no significant increase in bleeding or infection, according to the research.